Table 1. Baseline characteristics of the study population.

Features	Control	MCI	Dementia	p-value
N (Male/Female)	150(65/85)	89(36/53)	72(17/55)
Age (yr)	72.34±0.37	73.72±0.52	75.1±0.68	<0.001
Education	9.28±0.39	6.02±0.51	3.30±0.51	< 0.001
MMSE	27.33±0.17	24.65±0.34	15.92±0.68	<0.001
CDR	0.037±0.01	0.26±0.02	1.11±0.08	<0.001
sNotch1 (ng/mL)	2.81±0.17	2.23±0.07 a	2.1±0.07 b	0.015

Values are mean ± SEM

^acompared with control; p < 0.01,

^bcompared with control; p < 0.001

Key: MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination; CDR, clinical dementia rating; SEM, standard error of the mean.