Table 2. Characteristics of paediatric acute respiratory distress syndrome patients by paediatric intensive care unit survival status.
| Characteristic | Survived (n = 47) | Died (n = 31) | p-value |
|---|---|---|---|
| Age in months, median(IQR) | 11.0 (6.0–22.0) | 10.0 (6.5–36.0) | 0.63 |
| Unit GOSH n (%) | 10 (21) | 14 (45) | 0.04 |
| Unit ICH n (%) | 37 (79) | 17 (55) | |
| Diagnosis pneumonia n (%) | 37 (79) | 19 (61) | 0.27 |
| Diagnosis sepsis n (%) | 3 (6) | 3 (10) | |
| Diagnosis post surgery n(%) | 4 (9) | 3 (10) | |
| Diagnosis other n(%) | 3 (6) | 6 (19) | |
| Immune compromise n (%) | 5 (11) | 7 (23) | 0.20 |
| Premature n (%) | 23 (49) | 13 (42) | 0.64 |
| Direct injury n (%) | 40 (85) | 25 (81) | 0.76 |
| Infection n (%) | 39 (83) | 21 (68) | 0.17 |
| Prior steroid exposure n (%) | 6 (13) | 11 (36) | 0.02 |
| Inhaled nitric oxide use prior to initiation of steroid n (%) | 28 (60) | 16 (52) | 0.49 |
| PIM-3, median(IQR) n (%) | 0.07 (0.04–0.10) | 0.04 (0.02–0.08) | 0.02 |
| Oxygenation Saturation Index on day of start of steroids, median(IQR) | 12.3 (8.8–15.6) | 15.3 (12.0–21.4) | 0.01 |
| Days ventilated prior to start of steroids, median(IQR) | 9.0 (6.0–13.0) | 10.0 (6.0–12.5) | 0.72 |
| PELOD on day of starting steroid, median(IQR) | 2.0 (1.0–11.0) | 11.0 (10.0–12.5) | 0.02 |
| Neuro-muscular blockade prior to steroids (%) | 44 (94) | 30 (97) | 1 |
| Proning prior to steroids (%) | 29 (62) | 18 (58) | 0.11 |
| Fluid balance on day of starting steroids, ml/kg Median (IQR) |
90.6 (25.4–163.9) | 84.7 (20.5–168.6) | 0.78 |
| Response to steroids (≥ = 20% decrease in oxygenation index) n (%) | 34 (72) | 12 (39) | 0.004 |