Table 1. Baseline characteristics of NAFLD and non-NAFLD severe obese women.
| NAFLD (N = 40) | non-NAFLD (N = 67) | P value | |
|---|---|---|---|
| Age (y) | 46±6 | 47±7 | 0.652 |
| Caucasian Americans, n (%) | 29 (72.5) | 38 (56.7) | 0.191 |
| BMI (kg/m2) | 46.0±5.7 | 42.1±4.8 | <0.001 |
| Waist circumference (cm) | 126.2±10.9 | 119.2±11.0 | 0.002 |
| Systolic blood pressure (mmHg) | 136±10 | 135±16 | 0.667 |
| Diastolic blood pressure (mmHg) | 77±7 | 78±9 | 0.853 |
| Fasting blood glucose (mg/dL) | 97±12 | 90±10 | 0.005 |
| Fasting insulin (uU/L) | 18.1±9.1 | 14.3±7.9 | 0.027 |
| HOMA-IR | 4.4±2.5 | 3.3±1.9 | 0.012 |
| Total cholesterol (mg/dL) | 192±37 | 187±29 | 0.478 |
| HDL-C (mg/dL) | 47±8 | 50±12 | 0.093 |
| Triglyceride (mg/dL) | 134±59 | 114±60.0 | 0.092 |
| AST (U/L) | 25.3±7.0 | 24.1±4.8 | 0.35 |
| ALT (U/L) | 31.6±8.7 | 27.4±7.1 | 0.009 |
| Creatinine (mg/dL) | 0.78±0.13 | 0.83±0.14 | 0.078 |
| Metabolic syndrome, n(%) | 28 (70) | 34 (50.7) | 0.11 |
| Interleukin 6 (pg/mL) | 2.9±1.7 | 2.7±1.9 | 0.529 |
| Hs-CRP (mg/L) | 9.9±8.3 | 8.1±7.9 | 0.276 |
| Leptin (ng/mL) | 63.1±22.6 | 53.3±22.7 | 0.034 |
| Adiponectin (pg/mL) | 6386±4874 | 6603±4296 | 0.814 |
| HSI | 58.3±6.4 | 53.4±5.1 | <0.001 |
| LAPI | 101.7±41.9 | 79.0±41.8 | 0.008 |
| VAI | 1.7±1.0 | 1.5±1.2 | 0.28 |
| ZJU index | 58.7±5.8 | 53.9±4.8 | <0.001 |
NAFLD: non-alcoholic fatty liver disease; BMI: body mass index; HOMA-IR: homeostatic model assessment-insulin resistance; HDL-C: high-density lipoprotein-cholesterol; AST: aspartate aminotransferase; ALT: alanine aminotransferase; hs-CRP: high sensitivity-c reactive protein; HSI: hepatic steatosis index; LAPI: lipid accumulation production index; VAI: visceral adiposity index.