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Model 2-predicted effects of TDM in patients receiving posaconazole prophylaxis during GVHD. The effects of TDM-guided interventions with varied effectiveness are shown for quartiles of systemic posaconazole exposures (stacked bar graphs, left y axis) versus the average predicted probability ± standard deviation of clinical failure (plotted lines, right y axis) in patients receiving posaconazole suspension (a) or the extended-release tablet formulation (b).
