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Analysis of N-terminal APP fragments. Representative Western blot analysis of total secreted sAPP (detected by 22C11) and N-terminal APP fragments (N-APP20, detected with 22C11) in APPwt (lanes 3 + 4), or APP-S675E (lanes 5 + 6) expressing SK-N-AS cells, in the absence (lanes 3 + 5) or presence (lanes 4 + 6) of co-transfected meprin β.
