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. 2019 Oct 17;294(47):17837–17847. doi: 10.1074/jbc.RA119.009102

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© 2019 Wu et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 6. — USP3 and KLF5 protein expression levels are positively correlated in human TNBC. A, representative IHC results for USP3 and KLF5 in TNBC specimens. The negative results are shown in the left panel, and the positive results are shown in the right panel. Scale bar, 50 μm. B, a high expression level of USP3 mRNA is significantly associated with a short relapse–free survival of breast cancer patients who have received chemoradiotherapy. Kaplan–Meier plotter was used to analyze the breast cancer RNA-sequencing data from TCGA database. **, p < 0.01, t test. C, a high expression level of USP3 mRNA is significantly associated with a short distant metastasis-free survival of breast cancer patients who have received chemoradiotherapy. Kaplan–Meier plotter was used to analyze the breast cancer RNA-sequencing data from TCGA database. *, p < 0.05, t test.