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. 2019 Oct 17;294(47):17863–17874. doi: 10.1074/jbc.RA119.010284

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© 2019 Zhang et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 3. — Linc/circRNAs predicted to sponge multiple miRNAs during reprogramming. A, lincRNAs highly expressed during iPSCs reprogramming. B, circRNAs highly expressed during iPSCs reprogramming. * indicates p < 0.05. The error bars represent S.D. C, MEFs highly expressed miRNAs predicted to target linc/circRNAs. Almost all of the miRNAs shared complementary binding sites with the highly expressed linc/circRNAs with only a few exceptions. D, expression patterns of miRNAs that have been proven to inhibit cellular reprogramming. E, expression patterns of linc/circRNAs predicted to be targeted by the miRNAs inhibiting cellular reprogramming.