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. 2019 Nov 22;39(11):BSR20192298. doi: 10.1042/BSR20192298

Figure 1. The expression of miR-942 in BCa cell lines and its effect on the cell viability of BCa cells.

Figure 1

(A) QRT-PCR was performed to detect the expression of miR-942 in the whole blood of 31 BCa patients and 31 normal controls (n=3, **P<0.001, vs. normal). (B) Kaplan–Meier method was used to analyze the relationship between miR-942 and the overall survival rate of 60 BCa patients. (C) The expression of miR-942-3p with 1085 cancer and 104 normal samples in BRCA from database (P=0.001). (D) QRT-PCR was performed to detect the expressions of miR-942 in MCF-10A and BCa cell lines of normal breast epithelial cells (n=3, **P<0.001, vs. MCF-10A). (E,F) The transfection of miR-942 was detected by qRT-PCR (n=3, **P<0.001, vs Blank; ##P<0.001, vs MC or IC). (G,H) CCK-8 was used to detect cell viability (n=3, **P<0.001, vs Blank; ##P<0.001, vs MC or IC). (I–L) Colony formation assay was performed to detect the effect of miR-942 expression on cell proliferation (n=3, **P<0.001, vs Blank; ##P<0.001, vs MC or IC), U6 served as intrinsic parameters of experiment.