Table 2.

Linear regression models to explore a specific clinical or laboratory item associated with Cyr61.

Analytical data	β Coefficient	95% CI	p
Univariate analysis
Fever	−60.423	(−90.163, −30.684)	0.000
Arthralgia	−52.679	(−83.418, −21.939)	0.001
Arthritis	4.558	(−47.204, 56.320)	0.861
Skin rash	−43.682	(−75.057, −12.306)	0.007
Sore throat	−52.814	(−83.204, −22.425)	0.001
Lymphadenopathy	−30.018	(−62.330, 2.294)	0.068
Splenomegaly	−27.595	(−65.289, 10.099)	0.148
Hepatomegaly	−68.172	(−196.765, 60.420)	0.293
Pericarditis	−4.630	(−53.510, 44.251)	0.850
Pleuritis	−26.179	(−70.244, 17.887)	0.239
Pneumonia	−21.499	(−56.780, 13.783)	0.227
Myalgia	−13.684	(−52.818, 25.449)	0.487
Systemic score	−7.627	(−12.781, −2.472)	0.004
Leukocyte, × 109/L	−64.322	(−98.934, −29.709)	0.001
ESR, mm/h	−0.303	(−0.771, 0.165)	0.200
CRP, mg/L	−0.005	(−0.291, 0.280)	0.971
Ferritin, ng/ml	−0.003	(−0.009, 0.004)	0.414
IL−10, pg/ml	3.882	(−0.881, 8.645)	0.108
IL−1β, pg/ml	−22.028	(−64.310, 20.255)	0.301
IL−6, pg/ml	−0.402	(−1.381, 0.578)	0.415
TNF–a, pg/ml	0.252	(−2.815, 3.318)	0.870
IL−18, ng/ml	−0.027	(−0.095, 0.040)	0.424
Multivariate analysis
Fever	−4.416	(−141.063, −7.770)	0.029
Arthralgia	4.340	(−50.373, 59.054)	0.874
Skin rash	−17.042	(−67.220, 33.136)	0.498
Sore throat	−29.668	(−68.442, 9.106)	0.131
Systemic score	12.140	(−0.158, 24.438)	0.053
Leukocyte, × 109/L	−3.416	(−6.588, −0.244)	0.035

CRP, C-reactive protein; ESR, erythrocyte sedimentation rate.