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. 2019 Nov 20;7:295. doi: 10.3389/fcell.2019.00295

TABLE 2.

Gene Ontology (GO) terms enrichment analysis.

GO term Genes FDR
GO biological process
Fertilization 11 1.34E-10
ATP metabolic process 7 1.42E-04
Glycolytic process 4 1.62E-03
Sperm-egg recognition 4 2.37E-03
Acrosome reaction 3 5.30E-03
Spermatogenesis 7 1.15E-02
Gluconeogenesis 3 2.18E-02
Inner mitochondrial membrane organization 3 2.74E-02
GO cellular component
Sperm flagellum 8 5.84E-09
Acrosomal vesicle 8 8.16E-09
Mitochondrial proton-transporting ATP synthase complex 3 1.21E-03
Acrosomal membrane 3 1.28E-03
Extracellular vesicle 13 1.85E-03
Outer dense fiber 2 6.75E-03
Meiotic spindle 2 1.62E-02
Nucleus 23 1.71E-02
Sperm principal piece 2 3.91E-02

GO terms corresponding to biological processes and cellular components that are significantly enriched in the set of sperm proteins with altered abundance after incubation with capacitation medium and induction of the acrosome reaction. P-value < 0.05 after FDR correction.

HHS Vulnerability Disclosure