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. 2019 Nov 20;7:349. doi: 10.3389/fbioe.2019.00349

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Copyright © 2019 Wang, Paritala, Mendieta, Gu, Raffel, McGahan, Lloyd and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The highest values of wall shear stress (WSS) at bifurcation apex through one cardiac cycle in the tandem stenosis model and the three presumptive models by removing stenosis at different locations. Similar as the curves of massflow distribution, the difference of apex WSS between each model enlarged at systole period, and reduced at diastole period, The largest gap was found at around the ejection point (~0.3 s) between the tandem stenosis model (70.58 Pa) and the non-stenosis model (27.47 Pa).