Duplicates removed	102
Excluded during initial screening (e.g. press releases; news reports; not relevant drug/indication; preclinical study; reviews; case reports; not randomized trial)	358
Excluded during writing (e.g. reviews; duplicate data; small patient number; nonrandomized/phase I/II trials)	234
Cited efficacy/tolerability articles	44
Cited articles not efficacy/tolerability	22
Search Strategy: EMBASE, MEDLINE and PubMed from 2014 to present. Previous Adis Drug Evaluation published in 2014 was hand-searched for relevant data. Clinical trial registries/databases and websites were also searched for relevant data. Key words were dapagliflozin, Farxiga, Forxiga, BMS-512148, T2DM, type 2 diabete smellitus. Records were limited to those in English language. Searches last updated 10 June 2019