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. 2019 Nov 26;9:17605. doi: 10.1038/s41598-019-53985-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Individual changes in MEP amplitude over time. The dot pairs reflect MEP amplitude pre and post-tDCS for each participant in each of the 3 groups. Participants who showed a decrease in MEP between pre and post-tDCS are displayed in purple. *In the Motor Hotspot group, one participant presented a very strong effect post-tDCS. After running an outlier detection, this participant was removed from the rest of the analyses (indicated by the black arrow). M1: primary motor area, MEP: motor evoked potential, mV: millivolts, PMd: dorsal premotor cortex, tDCS: transcranial direct current stimulation.