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. 2019 Nov 26;9:17582. doi: 10.1038/s41598-019-53640-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Significant interactions of EV proteins and concentration and HOMA-B, cholesterol and race. Linear regression was used to analyze each EV protein or EV concentration on the interaction of (A) HOMA-B and (B) cholesterol, and race. P values for the interactions (P_i) and the R² for the model (R²_m) are indicated. Solid lines = African Americans (AfrAm) and dashed lines = whites. HOMA-B, homeostatic model assessment of β-cell function.