Table 1.

Levels of drinking-related and demographic variables at baseline, with inferential tests

	RET + PBO	RET + KET	No RET + KET	Total	Statistic	p	FDR α
Age	27.7 ± 8.33	26.5 ± 6.25	28.23 ± 9.57	27.48 ± 8.11	0.354	0.703	0.036
Gender (N F/M)	9	11	15	35	χ2(2) = 0.27	0.319	0.022
N smokers	18	19	19	56	χ2(2) = 0.095	0.954	0.047
AUDIT C	9.1 ± 1.03	9.2 ± 1.03	8.9 ± 1.18	9.07 ± 1.08	0.596	0.553	0.028
AUDIT total	22.17 ± 4.86	23.77 ± 5.15	20.47 ± 4.33	22.13 ± 4.93	3.559	0.033	0.003
SCID	0.93 ± 0.83	1.1 ± 0.92	0.77 ± 0.57	0.93 ± 0.79	1.344	0.266	0.019
Motivation to reduce	3.17 ± 0.59	3.13 ± 0.35	3.17 ± 0.38	3.16 ± 0.45	0.054	0.947	0.046
OCDS obsession	6.6 ± 3.31	6.57 ± 3.38	5.53 ± 3.45	6.23 ± 3.38	0.966	0.385	0.024
OCDS compulsion	11 ± 2.24	10.47 ± 2.66	10.93 ± 2.89	10.8 ± 2.59	0.371	0.691	0.033
OCDS total	17.6 ± 5.13	17.03 ± 5.52	16.47 ± 5.91	17.03 ± 5.49	0.315	0.731	0.038
TLFB total units (last 14 days)	135.2 ± 60.17	164.05 ± 86.82	130.04 ± 57.06	143.1 ± 70.16	2.098	0.129	0.008
TLFB daily units (last 14 days)	9.74 ± 4.28	11.76 ± 6.22	9.29 ± 4.08	10.26 ± 5.01	2.11	0.127	0.006
TLFB total units (last 7 days)	69.35 ± 32.21	86.73 ± 45.75	66.19 ± 32.08	74.09 ± 37.92	2.645	0.077	0.005
N drinking days (last 14 days)	11.07 ± 2.72	11.07 ± 2.78	11.2 ± 2.44	11.11 ± 2.62	0.025	0.975	0.050
N drinking days (last 7 days)	5.6 ± 1.33	5.63 ± 1.27	5.7 ± 1.47	5.64 ± 1.34	0.042	0.959	0.049
N binge days (last 14 days)	3.3 ± 3.31	4.73 ± 3.65	2.83 ± 2.32	3.62 ± 3.21	2.974	0.056	0.004
N binge days (last 7 days)	1.83 ± 1.79	2.6 ± 1.87	1.4 ± 1.35	1.94 ± 1.74	3.983	0.022	0.001
SOCRATES Recognition	24.87 ± 3.14	23.83 ± 3.42	23.33 ± 4.21	24.01 ± 3.64	1.4	0.252	0.017
SOCRATES Ambivalence	11.3 ± 2.9	10.97 ± 3.79	9.9 ± 3.45	10.72 ± 3.42	1.388	0.255	0.018
SOCRATES taking steps	21.77 ± 4.04	21.33 ± 4.04	20.87 ± 4.52	21.32 ± 4.18	0.343	0.71	0.037
BAS drive	11.1 ± 2.71	11.53 ± 2.98	10.57 ± 2.45	11.07 ± 2.72	0.951	0.39	0.027
BAS fun	13.27 ± 2.75	14.33 ± 1.6	13.77 ± 1.72	13.79 ± 2.11	1.957	0.147	0.009
BAS reward	16.63 ± 1.65	16.53 ± 2.62	16.3 ± 1.88	16.49 ± 2.07	0.201	0.819	0.041
BIS	20.87 ± 2.69	19.57 ± 2.81	19.97 ± 2.57	20.13 ± 2.72	1.837	0.165	0.013
BDI	15.47 ± 9.69	14.03 ± 8.58	11.3 ± 8.7	13.6 ± 9.07	1.657	0.197	0.014
CEOA sociability	25.77 ± 3.43	26.3 ± 4.16	24.43 ± 3.82	25.5 ± 3.86	1.904	0.155	0.012
CEOA tension reduction	7.3 ± 2.28	6.57 ± 1.81	7.03 ± 2.11	6.97 ± 2.07	0.96	0.387	0.026
CEOA liquid courage	12.93 ± 2.48	12.63 ± 2.98	12.23 ± 3.08	12.6 ± 2.84	0.453	0.637	0.031
CEOA sexuality	9.07 ± 2.8	8.3 ± 2.67	8.07 ± 2.43	8.48 ± 2.65	1.179	0.313	0.021
CEOA impairment	20.97 ± 5.24	21.3 ± 5.49	20.7 ± 3.98	20.99 ± 4.9	0.111	0.895	0.044
CEOA Risk/aggression	11.27 ± 3.04	12.03 ± 3.74	11.43 ± 3.46	11.58 ± 3.4	0.416	0.661	0.032
CEOA self perception	7.17 ± 2.37	6.77 ± 2.92	6 ± 2.23	6.64 ± 2.54	1.657	0.197	0.015
DTS TOLERANCE	2.92 ± 0.88	3.02 ± 1.01	2.93 ± 1.08	2.96 ± 0.98	0.091	0.913	0.045
DTS ABSORBANCE	2.79 ± 1.08	3.01 ± 1.12	2.92 ± 1.31	2.91 ± 1.16	0.273	0.762	0.040
DTS APPRAISAL	3.12 ± 0.96	3.55 ± 0.83	3.13 ± 1.09	3.27 ± 0.97	1.944	0.149	0.010
DTS REGULATION	3.1 ± 1.02	2.7 ± 1.08	2.88 ± 1.02	2.89 ± 1.04	1.115	0.332	0.023
DTS TOTAL	2.98 ± 0.81	3.07 ± 0.84	2.97 ± 0.98	3.01 ± 0.87	0.122	0.885	0.042
PANAS +VE	32.07 ± 7.91	33.47 ± 7.25	31.93 ± 8.11	32.49 ± 7.71	0.359	0.699	0.035
PANAS −VE	20.9 ± 6.38	21.1 ± 7.44	19.47 ± 6.91	20.49 ± 6.88	0.497	0.61	0.029

For continuous measures, the statistics given are mean ± SD, along with corresponding F values (DF 2, 87). For binary measures, Ns are given along with chi-square degrees of freedom and test values (denoted by χ²). “RET” = Retrieval, “KET” = Ketamine, “PBO” = Placebo. FDR α = False Discovery Rate alpha, calculated according to Benjamini and Hochberg³⁶. P-values represent One-way ANOVA on group differences. Significant uncorrected p-values at p < 0.05 are highlighted in bold. Only p-values lower than the associated FDR α are significant at FDR- corrected p < 0.05. The groups did not differ on any baseline variables according to FDR criteria