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. 2019 Nov 26;9:17629. doi: 10.1038/s41598-019-54016-1

Table 3.

Mean and (SD, coefficient of variation %) for each parameter (osteonal and interstitial separated).

Osteonal Interstitial Interaction Category/Region
Juvenile Adult p-values Juvenile Adult p-values Sense of interaction (Adult – Juvenile) (+/−) p-values
E*(GPa) 24.40 (1.93; 7.9%) 26.09 (1.83; 7.0%) 0.036 25.80 (1.93; 7.5%) 29.63 (1.11; 3.7%) <0.0001 <0.001
H/E* 0.0426 (0.0021; 4.9%) 0.0409 (0.0023; 5.6%) 0.0201 0.0429 (0.0019; 4.4%) 0.0418 (0.0026; 6.2%) ns 0.087 (ns)
Wplast/ Wtot 0.769 (0.007; 0.91%) 0.774 (0.009; 1.2%) ns 0.767 (0.008; 1.0%) 0.767 (0.007; 0.9%) ns 0.105 (ns)
Crystallinity (cm) 0.0360 (0.0024; 6.7%) 0.0379 (0.0011; 2.9%) 0.0144 0.0370 (0.0016; 4.3%) 0.0388 (0.0011; 2.8%) 0.003 0.619 (ns)
Carbonation 0.0066 (0.0008; 12.1%) 0.0078 (0.0005; 6.4%) 0.0002 0.0063 (0.0005; 7.9%) 0.0073 (0.0003; 4.1%) <0.0001 0.51 (ns)
Mineral/ Matrix 4.31 (0.44; 10.2%) 4.313 (0.345; 8.0%) ns 4.819 (0.36; 7.5%) 5.141 (0.284; 5.5%) 0.018 0.019
Mineral maturity 1.773 (0.235; 13.3%) 1.717 (0.271; 15.8%) ns 1.954 (0.195; 10.0%) 1.813 (0.276; 15.2%) ns 0.214 (ns)
Collagen maturity 3.769 (0.422; 11.2%) 3.984 (0.391; 9.8%) ns 4.516 (0.483; 10.7%) 4.305 (0.330; 7.7%) ns + 0.016
DMB (g/cm3) 1.027 (0.058; 5.6%) 1.079 (0.037; 3.4%) 0.0057 1.191 (0.047; 3.9%) 1.260 (0.029; 2.3%) <0.0001 0.145 (ns)

Difference Adult/Juvenile is indicated for each region, using a mixed model. The significance is also obtained (p) for each region, using a Mann-Whitney unpaired test. Interaction between Category and Region is obtained using a mixed model. The sense of the interaction (+/−) is indicated when the model is significantly relevant (p-values for interaction).