Fig. 1.
Development of the RWE Framework. RWE, real-world evidence. aGoogle.com and websites of relevant organizations: European Medicines Agency (http://www.ema.Europa.eu), US Food and Drug Administration (http://www.fda.gov), Association of the British Pharmaceutical Industry (http://www.abpi.org.uk), International Society for Pharmacoeconomics and Outcomes Research (http://www.ispor.org), Get Real (http://www.imi-getreal.eu), and Network for Excellence in Health Innovation (http://www.nehi.net). bExpertise in epidemiology, clinical outcomes assessment, health economics, outcomes research, market access, medical science, and medical affairs