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. 2019 Nov 26;9:17548. doi: 10.1038/s41598-019-54082-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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JZL184, an inhibitor for MAGL, suppresses social defeat stress-induced PGE₂ synthesis in subcortical tissues. The PGE₂ contents in subcortical (a) and cortical (b) tissues of wild-type mice treated with vehicle or JZL184 (40 mg/kg, i.p.) at least 60 min prior to single SDS. Brains were obtained immediately after single SDS and subjected to the PGE₂ measurement. *P < 0.05 for unpaired t test. Data are shown as means ± SEM.