Table 4.
Multivariate Associations of 3-Year Changes in Body Mass, Composition, and Strength Measures With Concurrent Changes in Urinary Incontinence and Nocturia.
| New or Worsening UI† | New or Worsening Nocturia‡ | |||
|---|---|---|---|---|
| No. of Events/Total | AOR (95% CI)* | No. of Events/Total | AOR (95% CI)* | |
| Body Mass Index, kg/m2 | ||||
| ≥5% decrease | 118/737 | 0.72 (0.43, 1.21) | 170/744 | 0.97 (0.65, 1.47) |
| <5% decrease or increase | 20/160 | Reference | 37/162 | Reference |
| ≥5% increase | 17/108 | 0.98 (0.56, 1.72) | 15/111 | 0.51 (0.30, 0.91)§ |
| Appendicular Lean Mass, kg | ||||
| ≥5% decrease | 91/564 | 0.89 (0.60, 1.33) | 121/570 | 1.12 (0.80, 1.57) |
| <5% decrease or increase | 43/300 | Reference | 72/304 | Reference |
| ≥5% increase | 5/25 | 1.27 (0.46, 3.5) | 3/26 | 0.45 (0.13, 1.54) |
| Appendicular Lean Mass/BMI | ||||
| ≥5% decrease | 91/580 | 0.98 (0.66, 1.45) | 127/583 | 0.98 (0.70, 1.38) |
| <5% decrease or increase | 45/290 | Reference | 65/297 | Reference |
| ≥5% increase | 3/19 | 0.94 (0.26, 3.5) | 4/20 | 0.83 (0.27, 2.6) |
| Total Fat, kg | ||||
| ≥5% decrease | 66/400 | 0.89 (0.57, 1.38) | 87/403 | 1.11 (0.76, 1.63) |
| <5% decrease or increase | 37/239 | Reference | 58/245 | Reference |
| ≥5% increase | 49/347 | 0.82 (0.55, 1.23) | 68/350 | 0.87 (0.61, 1.25) |
| Total Fat, % | ||||
| ≥5% decrease | 76/505 | 0.79 (0.45, 1.38) | 107/510 | 1.17 (0.75, 1.83) |
| <5% decrease or increase | 18/139 | Reference | 34/142 | Reference |
| ≥5% increase | 50/294 | 1.14 (0.77, 1.69) | 66/298 | 1.08 (0.76, 1.53) |
| Maximum Grip Strength, kg | ||||
| ≥5% decrease | 29/261 | 1.64 (1.04, 2.60)§ | 58/266 | 1.08 (0.76, 1.55) |
| <5% decrease or increase | 88/512 | Reference | 122/517 | Reference |
| ≥5% increase | 35/218 | 1.46 (0.85, 2.50) | 37/219 | 0.70 (0.44, 1.11) |
| Maximum Grip Strength/BMI | ||||
| ≥5% decrease | 33/253 | 1.36 (0.88, 2.10) | 60/260 | 0.92 (0.64, 1.32) |
| <5% decrease or increase | 83/500 | Reference | 112/504 | Reference |
| ≥5% increase | 35/236 | 1.16 (0.69, 1.94) | 44/236 | 0.74 (0.48, 1.15) |
| Quadriceps Strength, Nm/kg | ||||
| ≥5% decrease | 19/136 | 1.02 (0.60, 1.76) | 32/135 | 0.93 (0.60, 1.46) |
| <5% decrease or increase | 85/575 | Reference | 131/582 | Reference |
| ≥5% increase | 23/125 | 1.35 (0.69, 2.60) | 19/127 | 0.57 (0.30, 1.08) |
| Quadriceps Strength/BMI | ||||
| ≥5% decrease | 18/143 | 1.17 (0.67, 2.00) | 28/144 | 1.24 (0.78, 1.96) |
| <5% decrease or increase | 83/569 | Reference | 133/575 | Reference |
| ≥5% increase | 26/124 | 1.84 (0.95, 3.60) | 21/125 | 0.84 (0.45, 1.57) |
Abbreviations: UI Urinary Incontinence; BMI Body Mass Index; AOR Adjusted Odds Ratio; CI Confidence Interval; kg Kilogram; cm Centimeter; Nm Newton Meter.
Adjusted odds ratios were calculated using multivariate logistic regression models age, race, diabetes mellitus, and self-reported general health status.
New or worsening urinary incontinence was defined as at least monthly urinary incontinence among men who reported none at baseline or an increase in frequency among men with any incontinence at baseline.
New or worsening nocturia was defined as two or more voids per night among men who reported less than two voids per night or an increase in frequency to four or more voids per night among men with nocturia at baseline.
P < 0.05.