Fig. 2.

Mediation models demonstrating the total effect of injury severity (GCS) on verbal memory (LDFR; top) and the indirect effect of GCS on LDFR through fractional anisotropy (FA; lower eight) of the corpus callosum (CC), fornix (FX), right and left cingulum bundle (CB_R, CB_L), right and left perforant pathway (PP_R, PP_L), and right and left uncinate fasciculus (UF_R, UF_L). For each white matter pathway, bivariate and linear regression models were used to assess the bivariate relationship between GCS and FA, the bivariate relationship between FA and LDFR, holding GCS constant, and the direct effect of GCS on LDFR, holding FA constant. Each estimate along the path represents the standardized β coefficient from the regression model. Asterisks reflect statistically significant relationships (p < .05), and dashed arrows are indicative of indirect effects where GCS predicts LDFR through suppression by FA