Table 1 |.
Clinical characteristics of infant cohorts analyzed in this study
| Preterm Early Antibiotic Exposure Only (N=9) | Preterm Early + Subsequent Antibiotic Exposure (N=32) | Term Antibiotic-Naïve Infants (N=17) | |
|---|---|---|---|
| Birth weight, g, median (IQR) | 1080 (880, 1270) | 830 (698.75, 897.5) | 2529 (2359.5, 2966.5) |
| Gestational age at birth, weeks, median (IQR) | 27 (26, 27) | 25 (24, 26) | 36 (36,37) |
| Gender, M/F | 4/5 | 15/17 | 4/13 |
| Route of delivery, C-section/vaginal | 6/3 | 25/7 | 15/2 |
| Antibiotic exposure, n courses | |||
| Gentamicin | 9 | 74 | none |
| Ampicillin | 9 | 37 | none |
| Vancomycin | none | 67 | none |
| Clindamycin | none | 16 | none |
| Meropenem | none | 14 | none |
| Cefepime | none | 11 | none |
| Cefotaxime | none | 10 | none |
| Mupirocin | none | 7 | none |
| Trimethoprim-sulfamethoxazole | none | 4 | none |
| Ticarcillin-clavulanate | none | 3 | none |
| Oxacillin | none | 3 | none |
| Cefoxitin | none | 3 | none |
| Cefazolin | none | 2 | none |
| Amoxicillin | none | 2 | none |
| Metronidazole | none | 1 | none |
| Penicillin G | none | 1 | none |
| Bacterial culture positive, n | |||
| Blood | 0 | 22 | 0 |
| Tracheal | 0 | 30 | 0 |
| Urine | 0 | 17 | 0 |