Table 2.

Echocardiographic data of exercise-trained and sedentary mice

	Sham-Sed	Sham-ExT	CHF-Sed	CHF-ExT
n	5	6	6	5
EF, %	60.9 ± 2.3	58.3 ± 2.1	23.8 ± 4.8****	29.4 ± 3.8####
			(P < 0.0001)	(P < 0.0001)
FS, %	31.2 ± 3.3	29.2 ± 1.9	11.2 ± 2.7***	14.6 ± 2.4##
			(P = 0.0002)	(P = 0.0044)
EDV, μL	46.8 ± 11.9	63 ± 4.5	192.5 ± 34.2**	161 ± 23.6#
			(P = 0.0012)	(P = 0.0298)
ESV, μL	26 ± 5.9	25.2 ± 2.6	153.5 ± 30.3**	111.8 ± 24.3#
			(P = 0.0016)	(P = 0.0336)
LVAWd, mm	1.1 ± 0.1	1 ± 0.1	0.5 ± 0.1**	0.7 ± 0.1
			(P = 0.0027)
LVAWs, mm	1.4 ± 0.1	1.5 ± 0.1	0.6 ± 0.1**	0.8 ± 0.1##
			(P = 0.0017)	(P = 0.0055)
LVPWd, mm	0.9 ± 0.1	1 ± 0.1	0.9 ± 0.1	1 ± 0.1
LVPWs, mm	1.2 ± 0.2	1.2 ± 0.1	1.1 ± 0.1	1.2 ± 0.1
LVIDd, mm	3.5 ± 0.2	3.4 ± 0.4	6.1 ± 0.5**	5.6 ± 0.4##
			(P = 0.0014)	(0.0063)
LVIDs, mm	2.5 ± 0.2	2.6 ± 0.1	5.5 ± 0.6***	5.1 ± 0.5##
			(P = 0.0004)	(P = 0.0024)

Data are expressed as means ± SE; n = no. of mice. CHF-ExT, chronic heart failure exercise-trained; CHF-Sed, chronic heart failure sedentary; EDV, end-diastolic volume; EF, ejection fraction; ESV, end-systolic volume; FS, fractional shortening; LVAW, left ventricular anterior wall, LVPW, left ventricular posterior wall, LVID, left ventricular interior diameter; Sham-ExT, sham exercise-trained; Sham-Sed, sham sedentary; d, diastolic; s, systolic.

^**,

^***, and

^****CHF-Sed vs. Sham-Sed;

^#,

^##, and

^####CHF-ExT vs. Sham-ExT.