Table 3.
Sham-Sed | Sham-ExT | CHF-Sed | CHF-ExT | |
---|---|---|---|---|
n | 5 | 6 | 6 | 7 |
LVEDP, mmHg | 3.4 ± 0.8 | 2.8 ± 0.4 | 12.5 ± 1.4* | 11.6 ± 2.9# |
(P = 0.0181) | (P = 0.0122) | |||
dP/dt max, mmHg/s | 9,067 ± 479.1 | 9,366 ± 519.2 | 4,648 ± 679.2*** | 6,381 ± 487.7## |
(P = 0.0001) | (P = 0.0039) | |||
dP/dt min, mmHg/s | −9,553 ± 695.5 | −9,983 ± 662.2 | −5,080 ± 866.6** | −5,475 ± 579.4### |
(P = 0.0019) | (P = 0.0007) | |||
Heart rate, beats/min | 472 ± 35.6 | 466 ± 29.7 | 487 ± 28.5 | 504 ± 23.9 |
Data are expressed as means ± SE; n = no. of mice. CHF-ExT, chronic heart failure exercise-trained; CHF-Sed, chronic heart failure sedentary; LVEDP, left ventricular end diastolic pressure; Sham-ExT, sham exercise-trained; Sham-Sed, sham sedentary.
,
, and
comparisons between CHF-Sed and Sham-Sed;
,
, and
comparisons between CHF-ExT and Sham-ExT.