Cholesterol conversion or transport gene expression in peroxisome proliferator-activated receptor-α (PPARα) wild-type (Pparafl/fl) and PPARα hepatocyte-specific knockout (PparaHepKO) mice. Hepatic Abca1, Abcg1, Cd36, Cyp27a1, Cyp7a1, and Hmgcr1 mRNA levels in NFD (all circles) and HFD (all squares) in Pparafl/fl and PparaHepKO mice. Values are means ± SE; *P < 0.05 vs. NFD Pparafl/fl; ^P < 0.05 vs. NFD PparaHepKO; n = 16 and 13, Pparafl/fl NFD, HFD; n = 6 and 8, PparaHepKO NFD, HFD. n, number of mice.