Fig. 8.

Neonatal Fc receptor (FcRn) knockout (KO) podocytes have decreased synaptopodin expression at baseline and after treatment with proinflammatory stimuli. A: Western blot synaptopodin (Synpo) expression in wild type (WT) and FcRn KO podocytes treated with regular media (RM), IFNɣ, or IFNɣ plus 4-hydroxy-3-nitrophenylacetyl hapten-ovalbumin (NP-ova). B: quantitative analysis of synaptopodin expression normalized to β-actin as quantified by ImageJ (n = 6 experiments). Data are presented as means ± SE. In B, ns, not statistically significant, and *P < 0.05.