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. 2019 Aug 7;317(5):L569–L577. doi: 10.1152/ajplung.00080.2018

Fig. 1.

Fig. 1.

Effects of hypoxia on the level of cartilage oligomeric matrix protein (COMP) in the lungs of mice and organoid-cultured bovine arteries. Representative Western blot bands and quantitative analysis of COMP protein in the lungs from 3 wk chronic hypoxia (10% O2)-exposed male mice with pulmonary hypertension (PH) and control normoxic (21% O2) mice (**P < 0.01, PH mice versus control mice, Student’s t test, n = 5) (A); and in bovine pulmonary artery (BPA) organoid cultured under 3% or 21% O2 for 48 h (*P < 0 0.05, 3% versus 21% O2, paired t test, n = 5 (B); and in left anterior descending (paired t test, n = 5) (C); and left circumflex coronary arteries (n = 7) organoid cultured under 3% vs. 21% O2 (paired t test, n = 7) (D).