Interactions between 6 forms of myocardial cell death. The nature of the signals in the myocardium determines the cell death pathway a cell undergoes. However, oxidative damage to mitochondria can trigger multiple cell death pathways. Different colors denote different forms of cell death. DAMPs, damage-associated molecular patterns; LC3, microtubule-associated proteins 1A/1B light chain 3; MPT, Mitochondrial permeability transition; ROS, reactive oxygen species.