. 2019 Aug 28;317(5):F1142–F1153. doi: 10.1152/ajprenal.00276.2019

Table 1.

Baseline characteristics and single kidney function in study groups

	Lean	MetS	Lean + RAS	MetS + RAS
Body weight, kg^d	56.0 ± 6.2	90.5 ± 6.0^a	50.8 ± 6.4	91.2 ± 3.6^a
Mean arterial pressure, mmHg	98.4 ± 8.9	118.6 ± 15.1^a	119.6 ± 11.6^a	128.4 ± 8.4^a
Degree of stenosis, %^e	0	0	72.3 ± 10.2^a^,^b	77.5 ± 11.3^a^,^b
Total cholesterol, mg/dl^d	82.8 ± 7.8	422.2 ± 40.1^a	85.5 ± 6.7^b	417.3 ± 57.8^a^,^c
LDL cholesterol, mg/dl^d	33.4 ± 6.5	361.1 ± 63.4^a	66.8 ± 32.7^b	296.7 ± 52.8^a^,^c
Triglycerides, mg/dl^d	7.5 ± 1.9	17.3 ± 7.9^a	6.2 ± 1.2^b	13.3 ± 5.2^a^,^c
Fasting glucose, mg/dl^d	129.5 ± 14.7	113.0 ± 8.9	114.7 ± 12.0	108.5 ± 12.8
Fasting insulin, mU/ml^d	0.4 [0.3–0.5]	0.7 [0.7–0.8]^a	0.4 [0.3–0.4]^b	0.8 [0.7–0.8]^a^,^c
HOMA-IR score^d	0.6 [0.6–0.7]	1.9 [1.5–1.9]^a	0.6 [0.6–0.7]^b	1.8 [1.7–1.9]^a^,^c
Renal volume, ml^d^,^e	125.9 ± 12.3	217.9 ± 11.4^a	79.5 ± 10.3^a^,^b	169.1 ± 7.7^a^,^b^,^c
Renal blood flow, ml/min^d^,^e	522.2 ± 18.2	872.0 ± 87.8^a	331.9 ± 22.3^a^,^b	651.5 ± 11.2^a^,^b^,^c
Glomerular filtration rate, ml/min^d^,^e	74.7 ± 4.5	148.1 ± 6.1^a	39.2 ± 6.0^a^,^b	94.2 ± 4.8^a^,^b^,^c

Values are means ± SE; n = 7 each. Lean, lean diet fed; MetS, metabolic syndrome; RAS, renal artery stenosis; HOMA-IR, homeostasis model assessment of insulin resistance.

P < 0.05 vs. the Lean group;

P < 0.05 vs. the MetS group;

P < 0.05 vs. the Lean + RAS group.

MetS: significant effect of MetS (two-way ANOVA);

Ischemia: significant effect of ischemia (two-way ANOVA).