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. 2019 Aug 7;317(5):F1111–F1121. doi: 10.1152/ajprenal.00259.2019

Table 1.

Body weight, food intake, creatinine, blood urea nitroben, osmolality, and copeptin

NT Control Group DNP Group Heat Group DNP + Heat Group
Body weight before the experiment, g 27.77 ± 0.68 29.88 ± 2.05 29.34 ± 1.21 27.99 ± 0.93
Body weight after 10 days of the experiment, g 26.50 ± 0.55 27.57 ± 1.22 26.24 ± 0.80 25.63 ± 0.99
ΔBody weight after 10 days of the experiment, g −1.27 ± 0.30 −2.31 ± 0.86 −3.09 ± 0.55 −2.35 ± 0.20
Average Δbody weight after heat exposure/day, g −0.50 ± 0.19 −0.64 ± 0.07 −1.00 ± 0.19 −1.52 ± 0.12a
Food intake, g·mouse−1·day−1 3.22 ± 0.16 2.28 ± 0.12 2.19 ± 0.40 2.48 ± 0.30
Serum creatinine, mg/dl 0.79 ± 0.08 1.00 ± 0.04b 0.62 ± 0.05 0.96 ± 0.04c
Blood urea nitrogen, mg/dl 25.25 ± 1.38 25.57 ± 1.48 23.65 ± 0.80 36.79 ± 0.84d
Serum osmolality, mosm 323.2 ± 3.9 345.1 ± 3.5 329.6 ± 3.5 362.4 ± 13.7e
Serum copeptin, pg/ml 112.9 ± 11.2 115.2 ± 4.0 127.2 ± 5.4 158.7 ± 7.0f

Values are means ± SE. NT, nontreated; DNP, 2,4-dinitrophenol.

a

P < 0.001 vs. the NT control group and P < 0.01 vs. the DNP group;

b

P < 0.05 vs. the NT control group and P < 0.001 vs. the heat group;

c

P < 0.01 vs. the heat group;

d

P < 0.001 vs. the NT control, DNP, and heat groups;

e

P < 0.01 vs. the NT control group and P < 0.05 vs. the heat group;

f

P < 0.01 vs. the NT control and DNP groups and P < 0.05 between the DNP + heat group and the other groups.