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. 2019 Nov 11;28:101381. doi: 10.1016/j.redox.2019.101381

Fig. 1.

Fig. 1

Acetaldehyde induces cytotoxicity and impairs mitochondrial function. Primary cultures of cortical neurons (A) or SH-SY5Y cells (B, D and F) were exposed to various concentrations of acetaldehyde (0, 4, 20, 100, 500 μM) for 24 h, or exposed to 500 μM acetaldehyde for the indicated period of time (C, E and G). After the treatment, MTT assay (A, B, and C), JC-1 mitochondrial membrane potential assay (D, E) or ATP luminescent detection assay (F, G) was performed. Data represent mean ± SEM, n = 6 (A, B and C) or n = 3 (D, E, F and G). *p < 0.05 versus control.