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. 2019 Nov 15;24:e00401. doi: 10.1016/j.btre.2019.e00401

Fig. 2.

Fig. 2

Correlation of transgene expression levels between reporter gene, as a therapeutic gene, and monitor gene after gastric serosal surface instillation of naked pDNA (a) and intravenous injection of Lipoplex (b) in mice. Symbols and lines express luciferase expression in individual mice and regression lines, respectively. (a) Correlation between Fluc activity in the stomach and Gluc activity in plasma 6 h after instillation of naked pDNA onto the gastric serosal surface in mice. (b) Correlation between Fluc activity in the lung and Gluc activity in plasma 6 h after intravenous administration of lipoplex (a solution of 15 μg pcDNA3/Fluc and pcDNA3/Gluc in 200 μL (open circles), and 22.5 μg pcDNA3/Fluc and pcDNA3/Gluc in 300 μL (closed circles)) in mice.