Figure 2.

High dose of Y2R antagonist impaired motor function. I.t. injection of BIIE at 5 μg significantly decreased the fall off latencies in rotarod test compared with saline and low doses of BIIE (0.1 μg, 0.5 μg and 1 μg). n = 6 mice per group. ***p < 0.001, one-way ANOVA with Tukey’s post hoc test.