Fig. 4.
Effect of treatment with TAM, SIM and their combinations on extracellular level of MMP-2 and 9 using gelatin zymography and VEGF level in T47D cell line. Level of MMP-2 and 9 (A)and level of VEGF (B). Results are expressed as means ± SD of 2 independent experiments performed in duplicates. a: significantly different from the control group, b: significantly different from the TAM and c: significantly different from SIM at P value < 0.05. negative staining (0–25%) consider negative; (25–50%) mild; (50–75%) moderate; (75–100%) severe.
