Photomicrographs of EAC tumorsections stained by H&E(X160)treated with TAM, SIM, and their combinations.Effect of TAM, SIM and their combinations on TNF-α and NF-??B expression in EAC solid tumor. Immunohistochemical staining of TNF-α in EAC solid tumor sections (X40) control (A), TAM (2.5 mg/kg) (B), SIM (2 mg/kg) (C) and combination(D). Immunohistochemical staining of NF-??B in EAC solid tumor sections(X40).Control (E), TAM (2.5 mg/kg) (F), SIM (2 mg/kg) (G)and combination (H).