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. 2019 Nov 26;93(24):e00980-19. doi: 10.1128/JVI.00980-19

TABLE 1.

HLA class I allele restriction and demographic and clinical data of MS brain tissue donors

Donor IDa Donor HLA class I allele(s) Sex/age at deathb (yr) Age at onset (yr) Disease duration (yr) Therapyc Cause of deathd Postmortem delay (h)
MS79 A*0201 F/49 25 24 Courses of ACTH, azathioprine, and methylprednisolone over 2 yr MS 7
MS92 B*0801 F/37 20 17 None reported MS 26
MS121 B*0801 F/49 35 14 Methylprednisolone for 1 yr MS 24
MS154 B*0801 F/35 23 12 None reported MS 12
MS180 B*0801 F/44 26 18 None reported MS 9
MS234 B*0801 F/39 24 15 None reported MS 15
MS286 A*0201 M/46 30 16 None reported MS 7
MS289 A*0201, B*0702 M/45 27 18 None reported MS 9
MS330 B*0702 F/59 20 39 None reported MS 21
MS342 A*0201, B*0702 F/35 30 5 None reported MS 9
MS352 B*0801 M/43 25 18 Methylprednisolone and alemtuzumab (one course each) 10 yr before death MS 26
MS356 B*0702 F/45 29 16 None reported MS 10
a

All MS donors were in the progressive phase of the disease.

b

F, female; M, male.

c

ACTH, adrenocorticotropic hormone.

d

MS is stated as a cause of death where death occurred as a direct result of MS or any related disability.