Table 3.
Multivariate analysis of repeated measures before and after adjuvant treatment in patients with colon and breast cancer and curative surgery for the cancer
| Scales | Colon cancer (n = 114) | Breast cancer (n = 89) | ANOVA results, F | ||||
|---|---|---|---|---|---|---|---|
| Pre Mean (SD) | Post Mean (SD) | Pre Mean (SD) | Post Mean (SD) | Time x tumor | Time | Tumor site | |
| Psy. distress (BSI) a | 62.3 (6.4) | 64.6 (6.7) | 64.4 (7.4) | 65.9 (6.8) | 0.295 | 11.223** | 4.691 |
| Anxiety | 60.3 (7.1) | 60.0 (7.2) | 62.1 (8.3) | 61.1 (7.6) | 1.662 | 0.414 | 2.426 |
| Depression | 59.4 (5.5) | 60.1 (5.7) | 60.5 (6.2) | 60.2 (5.7) | 1.246 | 0.248 | 0.845 |
| Somatization | 59.9 (6.1) | 64.4 (7.2) | 61.3 (6.7) | 65.9 (7.1) | 0.034 | 80.033** | 3.112 |
| Coping with cancer (M-MAC) b | |||||||
| Adaptive | 64.8 (18.1) | 63.2 (19.5) | 66.3 (14.2) | 59.6 (17.8) | 4.199 | 11.602** | 0.205 |
| Fighting spirit | 77.2 (18.2) | 72.4 (20.9) | 77.7 (16.9) | 71.8 (21.2) | 0.160 | 13.826** | 0.002 |
| Cognitive Avoidance | 51.4 (26.6) | 52.3 (28.1) | 53.1 (25.2) | 48.7 (25.3) | 2.056 | 0.916 | 0.084 |
| Fatalism | 35.8 (20.6) | 63.7 (22.3) | 38.7 (17.9) | 58.7 (22.1) | 6.039 | 13.707** | 0.165 |
| Maladaptive | 29.3 (18.5) | 23.2 (18.2) | 29.1 (19.3) | 27.2 (20.3) | 2.606 | 9.179** | 0.612 |
| Helplessness | 20.1 (19.1) | 13.7 (17.5) | 16.1 (17.6) | 14.3 (19.5) | 2.402 | 7.509** | 0.610 |
| Anxious preoccupation | 38.3 (22.9) | 32.5 (22.5) | 42.0 (26.0) | 39.6 (24.7) | 1.203 | 6.904** | 3.124 |
| Quality of life (EORTC-QLQ-C30) b | |||||||
| Functional scale | 83.5 (11.4) | 77.9 (13.7) | 82.5 (10.4) | 75.5 (14.3) | 0.572 | 49.525** | 1.046 |
| Symptom scale | 83.3 (10.3) | 84.1 (13.4) | 83.1 (13.4) | 82.4 (11.7) | 0.758 | 0.008 | 0.412 |
| Health Status scale | 59.8 (18.1) | 56.4 (19.4) | 62.8 (17.1) | 57.0 (20.3) | 0.494 | 7.065** | 0.710 |
| Quality of life scale | 75.3 (11.1) | 72.6 (12.1) | 76.6 (10.6) | 71.3 (12.6) | 1.238 | 16.877** | 0.021 |
These analyses were age-adjusted.
Abbreviations: BSI Brief Symptom Inventory, EORTC-QLQ-C30 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, M-MAC Mini-Mental Adjustment to Cancer, Pre before adjuvant treatment, Post after adjuvant treatment, Psy psychological, SD Standard Deviation
*p < 0.01 (two-tailed), ** p < 0.001 (two-tailed)
a T score. b Scale from 0 to 100