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. 2019 Nov 27;21:247. doi: 10.1186/s13075-019-2041-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Triggers of Wnt/β-catenin signaling in SFZ cells. a mRNA levels of Wnt ligands in SFZ cells. b mRNA levels of Prg4, Ctnnb1, Axin2, and Wnt ligands in SFZ cells loaded with cyclic tensile strain. c mRNA levels of Prg4, Ctnnb1, and Axin2 in SFZ cells treated with 100 ng/ml recombinant human (rh) WNT5A, WNT5B, WNT9A, or vehicle for 1 week. All data are expressed as mean ± SD of three biologically independent samples per group. *P < 0.05 and **P < 0.01 versus vehicle or 0 h (one-way ANOVA followed by Tukey’s correction)