Table 1.
Clinical characteristics and outcomes stratified by ST resolution (STR)
| Variable | STR ≥ 70% n = 77 (22%) | 30% ≤ STR < 70% n = 160 (46%) | STR < 30% n = 112 (32%) | P |
|---|---|---|---|---|
| Patient characteristics | ||||
| Age (years) | 61.2 ± 7.3 | 62.1 ± 8.4 | 60.0 ± 7.8 | 0.12 |
| Male (%) | 75.3 | 74.4 | 71.4 | 0.15 |
| Smoking (%) | 55.8 | 52.5 | 58.0 | 0.26 |
| Hypercholesterolemia (%) | 41.6 | 37.5 | 40.2 | 0.54 |
| Diabetes mellitus (%) | 9.1 | 12.5 | 21.4 | 0.03 |
| Renal insufficiency (%) | 5.2 | 5.6 | 8.0 | 0.09 |
| Previous infarction (%) | 6.5 | 7.5 | 8.9 | 0.14 |
| Heart rate (bpm) | 75.6 ± 8.2 | 72.0 ± 9.3 | 77.9 ± 7.7 | 0.87 |
| Killip class > 1 (%) | 11.4 ± 3.2 | 15.8 ± 3.8 | 19.4 ± 4.6 | 0.08 |
| Left ventricular ejection fraction (%) | 56.6 ± 7.9 | 52.0 ± 8.2 | 42.4 ± 7.6 | 0.02 |
| Home medication (%) | ||||
| Aspirin | 21.3 | 24.1 | 22.6 | 0.12 |
| Clopidogrel | 6.2 | 5.7 | 5.2 | 0.64 |
| Statins | 16.4 | 17.7 | 15.7 | 0.55 |
| β blockers | 12.4 | 14.1 | 13.8 | 0.76 |
| ACE inhibitors/ATII antagonists | 27.3 | 24.5 | 25.7 | 0.14 |
| Ischemia characteristics | ||||
| Total ischemic time (min) * | 445.6 ± 46.2 | 481.7 ± 48.4 | 473.0 ± 41.3 | 0.07 |
| Anterior MI (%) | 45.5 | 40.0 | 42.8 | 0.13 |
| Non-anterior MI (%) | 54.5 | 60.0 | 57.2 | 0.45 |
| Maximal cTnI (ng/mL) | 0.54 ± 0.08 | 2.82 ± 0.25 | 6.03 ± 0.52 | < 0.001 |
| Creatine kinase-MB (U/L) | 54.0 ± 6.3 | 168.0 ± 14.4 | 276.0 ± 26.3 | < 0.01 |
| Multi vessel disease (%) | 35.0 | 32.5 | 33.9 | 0.41 |
| Initial TIMI flow (%) | ||||
| 0 | 14.3 | 36.3 | 80.4 | < 0.001 |
| 1 | 7.8 | 9.4 | 6.3 | 0.45 |
| 2 | 26.0 | 26.9 | 9.8 | < 0.001 |
| 3 | 51.9 | 27.5 | 3.5 | < 0.001 |
| Baseline Rentrop classification (%) | ||||
| 0–1 | 62 | 66 | 59 | 0.23 |
| 2–3 | 38 | 34 | 41 | 0.26 |
| Treatment characteristics (%) | ||||
| Stent implantation | 93.5 | 95.6 | 95.5 | 0.54 |
| Platelet glycoprotein IIb/IIIa inhibitors | 42.9 | 48.8 | 57.1 | 0.03 |
| Post-procedural TIMI flow (%) | ||||
| 0 | 1.3 | 1.2 | 2.7 | 0.02 |
| 1 | 1.3 | 4.4 | 8.0 | 0.01 |
| 2 | 6.5 | 9.4 | 21.4 | 0.01 |
| 3 | 90.9 | 85.0 | 67.9 | 0.03 |
| Medical treatment at discharge (%)* | ||||
| Aspirin | 100 | 100 | 100 | 1 |
| Clopidogrel | 100 | 100 | 100 | 1 |
| Statins | 100 | 100 | 100 | 1 |
| β-blockers | 96.1 | 98.1 | 94.4 | 0.42 |
| ACE inhibitor/ATII antagonists | 64.9 | 59.5 | 65.4 | 0.56 |
cTnI: cardiac troponin I; MI: myocardial infarction; STR: ST resolution; TIMI: thrombolysis in myocardial infarction. * interval from symptom onset to balloon dilation. ACE: angiotensin converting enzyme; ATII: angiotensin receptor subtype II; CV: cardiovascular; STR: ST resolution; TIMI: thrombolysis in myocardial infarction