Fig. 3.

FOXG1 enhances metastasis of HCC cell lines in vivo. a Representative bright-field image of the lungs. On day 35, mice that received Huh7/vector or Huh7/FOXG1 cells were anesthetized and sacrificed, and the lungs were collected. Arrows indicate surface metastatic nodules. b Number of visible surface metastatic lesions in mice (n = 5 per group) that received tail vein injection of Huh7/vector or Huh7/FOXG1 cells. c Body weight of BALB/C mice that received transplants of Huh7/vector or Huh7/FOXG1 cells. d Lung metastases in mice implanted with Huh7/vector or Huh7/FOXG1 cells were confirmed by hematoxylin and eosin (H&E) staining