Figure 1.

Schematic description of molecular targets of pomegranate with respect to cancer metastasis. CXCR4: C-X-C chemokine receptor type 4; HAMMR: Hyaluronic acid-mediated motility receptor/CD168; IL: Interleukin; IP-10: Induced protein-10; MARCKS: Myristoylated alanine-rich protein kinase C substrate; MCP: Monocyte chemoattractant protein; MIP-1: Macrophage inflammatory protein-1; MMP: Matrix metalloproteinase; RANTES: Regulated on activation, normal T Cell expressed and secreted; SDF1: Stromal cell-derived factor 1; TNC: Tenascin C; TNF-α: Tumor necrosis factorα; VCAM-1: Vascular cell adhesion molecule-1; VEGF: Vascular endothelial growth factor; ZO: Zonula occludens