Table 4.
Association of sarcopenia components with uric acid in females and males, separately
| Dependent variables | Independent variablesa | Females | Males | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Subjects with ≤medianb | Subjects with >medianb | Crude model Ic | Crude model IIc | Crude model IIIc | Subjects with ≤medianb | Subjects with >medianb | Crude model Ic | Crude model IIc | Crude model IIIc | ||
| SMI | (n = 75) | (n = 72) | (n = 118) | (n = 113) | |||||||
| G1 | 20 (54.1) | 17 (45.9) | 2.08 (0.81, 5.32) | 1.24 (0.50, 3.09) | 0.64 (0.25, 1.62) | 30 (52.6) | 27 (47.4) | 1.32 (0.63, 2.77) | 1.51 (0.73, 3.14) | 0.63 (0.30, 1.33) | |
| G2 | 24 (64.9) | 13 (35.1) | 3.27 (1.25, 8.52)d | 1.95 (0.77, 4.96) | 1 | 37 (63.8) | 21 (36.2) | 2.10 (0.99, 4.43) [P = .052] | 2.40 (1.14, 5.04)d [P = .021] | 1 | |
| G3 | 18 (48.6) | 19 (51.4) | 1.68 (0.66, 4.28) | 1 | 25 (42.4) | 34 (57.6) | 0.88 (0.42, 1.83) | 1 | |||
| G4 | 13 (36.1) | 23 (63.9) | 1 | 26 (45.6) | 31 (54.4) | 1 | |||||
| Handgrip strength | (n = 73) | (n = 74) | (n = 116) | (n = 115) | |||||||
| G1 | 22 (59.5) | 15 (40.5) | 0.43 (0.17, 1.11) | 0.72 (0.29, 1.81) | 0.65 (0.26, 1.62) | 27 (47.4) | 30 (52.6) | 0.93 (0.45, 1.94) | 1.31 (0.63, 2.74) | 0.51 (0.24, 1.08) | |
| G2 | 18 (48.6) | 19 (51.4) | 0.67 (0.26, 1.70) | 1.11 (0.45, 2.77) | 1 | 37 (63.8) | 21 (36.2) | 1.82 (0.87, 3.85) | 2.57 (1.22, 5.42)d [P = .013] | 1 | |
| G3 | 19 (51.4) | 18 (48.6) | 0.60 (0.24, 1.53) | 1 | 24 (40.7) | 35 (59.3) | 0.71 (0.34, 1.48) | 1 | |||
| G4 | 14 (38.9) | 22 (61.1) | 1 | 28 (49.1) | 29 (50.9) | 1 | |||||
| Whole‐body total BMD | (n = 72) | (n = 75) | (n = 116) | (n = 115) | |||||||
| G1 | 22 (59.5) | 15 (40.5) | 3.33 (1.27, 8.76)d [P = .015] | 1.25 (0.50, 3.13) | 1.39 (0.55, 3.49) | 33 (57.9) | 24 (42.1) | 1.33 (0.63, 2.78) | 1.88 (0.89, 3.91) | 1.38 (0.66, 2.87) | |
| G2 | 19 (51.4) | 18 (48.6) | 2.40 (0.92, 6.25) | 0.90 (0.36, 2.24) | 1 | 29 (50) | 29 (50.0) | 0.97 (0.46, 2.01) | 1.36 (0.66, 2.82) | 1 | |
| G3 | 20 (54.1) | 17 (45.9) | 2.67 (1.02, 6.98)d [P = .045] | 1 | 25 (42.4) | 34 (57.6) | 0.71 (0.34, 1.48) | 1 | |||
| G4 | 11 (30.6) | 25 (69.4) | 1 | 29 (50.9) | 28 (49.1) | 1 | |||||
| SPPB score | (n = 105) | (n = 42) | (n = 138) | (n = 93) | |||||||
| G1 | 26 (70.3) | 11 (29.7) | 1.04 (0.38, 2.83) | 0.76 (0.27, 2.13) | 1.00 (0.37, 2.71) | 34 (59.6) | 23 (40.4) | 1.07 (0.51, 2.27) | 1.09 (0.52, 2.28) | 0.84 (0.40, 1.79) | |
| G2 | 26 (70.3) | 11 (29.7) | 1.04 (0.38, 2.83) | 0.76 (0.27, 2.13) | 1 | 37 (63.8) | 21 (36.2) | 1.28 (0.60, 2.71) | 1.30 (0.62, 2.73) | 1 | |
| G3 | 28 (75.7) | 9 (24.3) | 1.37 (0.49, 3.84) | 1 | 34 (57.6) | 25 (42.4) | 0.99 (0.47, 2.07) | 1 | |||
| G4 | 25 (69.4) | 11 (30.6) | 1 | 33 (57.9) | 24 (42.1) | 1 | |||||
a
Independent variable was set as uric acid, and it was subgrouped into 4 groups, G1 (≤1st quartile), G2 (>1st quartile and ≤median), G3 (>median and ≤3rd quartile), and G4 (>3rd quartile). The population was divided by sex.
b
Indicates the numbers of subjects with median value given dependent variables by sex.
c
Crude models I, II, and III were performed for the association of dependent variables (≤median) and independent variables utilizing the binary logistic regression model with setting the reference group as uric acid G4, G3, and G2, separately. Results were presented as odds ratio (95% CI).
d
P < .05 indicates significant association.