Table 2.

Alteration region of gray matter volume in IBS patients and HCs

Location			Regions	P value	Voxels (mm3)	t value
X	Y	Z
31.5	−57	−36	Anterior cerebellum lobe, posterior cerebellar lobe, cerebellum nodules	<0.01	605	3.3454
21	−100.5	−7.5	Occipital lobe, precentral gyrus, inferior occipital gyrus	<0.01	243	3.5038
−15	−25.5	−9	Limbic lobe, hippocampus, insula, left supramarginal gyrus	<0.01	77	3.4123
49.5	−66	10.5	Middle temporal gyrus	<0.01	402	3.0391
34.5	48	7.5	Frontal lobe, middle frontal gyrus	<0.01	77	2.7774

HCs, healthy controls; IBS, irritable bowel syndrome.