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. 2019 Oct;189(10):1945–1952. doi: 10.1016/j.ajpath.2019.06.004

Figure 5.

Figure 5

Lysyl oxidase propeptide (LOX-PP) compromised AKT activation in rat retinas. A: Representative Western blot image shows protein expression of phospho- (p-)AKT, total AKT, and β-actin in retinas of wild-type (WT) rats, diabetic (DM) rats, WT rats intravitreally injected with recombinant LOX-PP (WT+rLOX-PP IV), and WT rats intravitreally injected with phosphate-buffered saline (WT+PBS IV). B: Graphical illustration of cumulative data shows LOX-PP could compromise AKT activation in rat retinas. Data are expressed as means ± SD. *P < 0.05 versus WT.