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. 2019 Nov 20;10:2669. doi: 10.3389/fimmu.2019.02669

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Copyright © 2019 Nagaoka, Kanoi, Jinoka, Morita, Arumugam, Palacpac, Egwang, Horii, Tsuboi and Takashima.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Seroprevalence (%) of ecto-PfMSP10 and PfMSP10 regions in different age groups; 6–10 years (n = 22), 11–16 years (n = 22), and 16–20 years (n = 22). All PfMSP10 regions were immunogenic in natural infections. (B) Kaplan–Meier plot of the probability of remaining free from clinical malaria during the 1-year follow-up in respect to antibodies against PfMSP10 R1. Individuals with high antibody levels, above population median (red), are compared to those with low levels (black) (p < 0.05).