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. Author manuscript; available in PMC: 2019 Nov 27.
Published in final edited form as: Prog Mol Biol Transl Sci. 2009 Oct 7;87:343–382. doi: 10.1016/S1877-1173(09)87010-5

Fig. 1.

Fig. 1.

Schematic representations of ASC-2 and MLL4. Various domains that include the AD1–3, DD (dimerization domain), and ARID (AR-interacting domain) in ASC-2, as well as the PHD finger, HMG box, and SET domains in MLL4, are as indicated. The SET domain in MLL3/4 also serves as a docking site for a subcomplex consisting of WDR5 (W)-RbBP5 (R)-ASH2L (A).