Fig 3. AcrB R717Q increases efflux of macrolides in E. coli and Salmonella Typhi strains.
Quantification of results obtained from three biological replicates for (A) disc diffusion and (B) E-strip assays are shown for E. coli BW25113 ΔacrB transformed with different plasmids. (C) Quantification of results obtained from at least three biological replicates from azithromycin E-strip assay in Typhi strain 4119. One way-ANOVA with multiple comparisons was used to test statistical significance. ns: p>0.05; **: p ≤ 0.01; ***: p ≤ 0.001, ****: p ≤ 0.0001.