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. 2019 Nov 15;15(11):e1007926. doi: 10.1371/journal.ppat.1007926

Fig 9. NMDS analysis of fecal microbial communities during low dose and trickle T. muris infection.

Fig 9

(A) NMDS plot of microbial communities during T. muris low dose infection. Naïve mice (blue) were compared to mice trickled with T. muris (purple) at 9 and 11 weeks post infection (◯ & ☐). Infection and time drove significant changes in microbiome composition (p = 0.001 & p = 0.05) assessed by PERMANOVA. (B) NMDS plot of microbial communities during T. muris trickle infection. Naïve mice (blue) were compared to mice trickled with T. muris (red) at 9 and 11 weeks post infection (◯ & ☐). Infection drove a significant change in microbiome composition (p < 0.004) assessed by PERMANOVA. Axes represent a scale of Euclidian distances between samples where the centre is zero. Stress measures quality of fit (< 0.1 indicates a very good fit). (C & D) Alpha diversity of (C) low dose and (D) trickle infected mice given calculated in R by Shannon diversity test using the Vegan package. Significance is calculated by two-way ANOVA. Data presented as mean, * = p<0.05, ** = p<0.01, **** = p<0.0001.