(A) Event-free survival (EFS) and overall survival (OS) for evaluable, intermediate-risk patients (n = 404). (B) EFS for evaluable, intermediate-risk patients according to initial treatment group assignment (n = 404; P = .0012). (C) OS for evaluable, intermediate-risk patients according to initial treatment group assignment (n = 404; P < .001). (D) EFS for evaluable, intermediate-risk patients according to 1p loss of heterozygosity (LOH) status (n = 341; P = .41). (E) OS for evaluable, intermediate-risk patients according to 1p LOH status (n = 341; P = .44). (F) EFS for evaluable, intermediate-risk patients according to 11q LOH status (n = 340; P = .02). (G) OS for evaluable, intermediate-risk patients according to 11q LOH status (n = 340; P = .09).