Skip to main content
. Author manuscript; available in PMC: 2019 Nov 27.
Published in final edited form as: ACS Appl Mater Interfaces. 2019 Feb 21;11(9):8849–8857. doi: 10.1021/acsami.8b21270

Figure 2: Ligand density-induced YAP nuclear translocation requires cytoskeletal tension.

Figure 2:

(a) YAP (green) and F-Actin (red) localization after the disruption and subsequent rescue of cytoskeletal tension through addition and removal of blebbistatin and with ROCK-inhibitor Y27632. hMSCs were cultred on soft and stiff substrates with low and high ligand densities. Scale bar: 30 μm. (b) Quantification of YAP nuclear localization, ****p<0.0001.