Table 1.
Demographic and clinical characteristics of 56 TDPD patients and 23 healthy controls.
| TDPD-SD | TDPD-NSD | HC | F/χ2/H/t | p-value | |
|---|---|---|---|---|---|
| Age | 65.50 (7.73) | 63.04 (5.65) | 61.43 (8.46) | 2.12 | 0.13a |
| Gender (male, %) | 42.86% | 75.00% | 52.17% | 5.55 | 0.062b |
| Education | 11.28 (3.12) | 11.46 (3.41) | 12.72 (2.71) | 1.556 | 0.22a |
| HAM-D | 8.59 (4.25) | 7.08 (5.08) | 6.22 (2.33) | 2.39 | 0.099c |
| MMSE | 27.38 (3.15) | 27.38 (2.53) | 26.26 (2.14) | 1.38 | 0.26c |
| PSQI | 11.50 (1.39) | 1.63 (0.88) | 32.48 | 0.037d | |
| PDSS | 110.19 (16.30) | 129.54 (11.62) | −4.66 | 0.039d | |
| H & Y | 1.91 (0.50) | 2.04 (0.62) | −0.69 | 0.49d | |
| Disease duration (years) | 5.44 (3.88) | 5.17 (3.91) | −0.14 | 0.89d | |
| MDS-UPDRS | 49.66 (21.83) | 44.71 (20.77) | −0.70 | 0.48d | |
| MDS-UPDRS III | 28.50 (16.12) | 25.79 (13.36) | −0.44 | 0.66d |
TDPD-SD, tremor-dominant Parkinson’s disease with sleep disorder; TDPD-NSD, tremor-dominant Parkinson’s disease with no sleep disorder; HC, healthy controls; HAM-D, Hamilton Depression Rating Scale; MMSE, Mini-Mental State Examination; H & Y, Hoehn & Yahr scale; PSQI, Pittsburgh Sleep Quality Index; PDSS, Parkinson’s Disease Sleep Scale; MDS-UPDRS, Unified Parkinson’s Disease Rating Scale. Values are given as the mean (SD) except for sex, which is presented as the proportion of male patients. Group differences were tested using SPSS software. Differences were considered statistically significant when p < 0.05. ap-value obtained with one-way analysis of variance. The test statistic of the method is called the F-statistic. bp-value obtained with chi-squared test. The test statistic of the method is called the χ2 statistic. cp-value obtained with the Kruskal–Wallis test. The test statistic of the method is called the H statistic. dp-value obtained with independent t-test for continuous variables. The test statistic of the method is called the t-statistic.